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PCOG LEC FINALS


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Natural Fibres used for the preparation of Surgical Dressings are obtained from
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Plants Animals Minerals Synthetic & other Fibres

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PCOG LEC FINALS - Marcador

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PCOG LEC FINALS - Detalles

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Surgical Dressings Functions Why do we use it?
1 Reduce or prevent infection 2 Mechanical support to the tissues 3 Arrest bleeding 4 Protection to healing wound RAMP
Pharmacopoeial Requirements for Surgical Dressings
1 Sterilized before use 2 Stored in dry, well-ventilated place below 25 C 3 Permitted antiseptics in prescribed concentrations be used 4 Dyed unless mentioned in monograph 5 Adhesive products not allowed to freeze 6 No loose threads, fibre ends
1 Types of Dressing
1 Natural and Manmade
1 Cheap and used a lot as filtering medium and in surgical dressings 2 Example 3 Source
1 Vegetable fibres 2 Cotton (syn. Raw Cotton, Purified Cotton, Absorbent Cotton) 3 Epidermal Trichomes covering seeds of Gossypium herbaceum, Fam Malvaceae
Vegetable Fibres List
1 JUTE 2 FLAX 3 HEMP 4 CHEMICAL WOOD PULP
Vegetable Fibres List
1 JUTE 2 FLAX 3 HEMP 4 CHEMICAL WOOD PULP
Animal Fibres List
1 WOOL 2 SILK
Animal Fibres List
1 WOOL 2 SILK
What are the parts of Surgical Dressings?
1 Wound facing layer 2 Absorbent layer 3 Outer layer WAO
1 Cheap and used a lot as filtering medium and in surgical dressings 2 Example 3 Source
1 Vegetable fibres 2 Cotton (syn. Raw Cotton, Purified Cotton, Absorbent Cotton) 3 Epidermal Trichomes covering seeds of Gossypium herbaceum, Fam Malvaceae
JUTE
Phloem fibres from stem bark of Corchorus capsularis, C. olitorius, Fam.Tiliaceae
FLAX
Pericyclic fibres of the stem of Linum usitatissimum Fam.Linaceae
HEMP
Pericyclic fibres of Cannabis sativa stem Fam. Cannabinaceae
CHEMICAL WOOD PULP (WOOD)
Delignified wood produced by “Sulphite process” to leave the cellulose
WOOL
From the fleece of the sheep Ovis aries, Fam Bovidae
SILK
Fibre from the cocoons of silk worms Bombyx mori, Fam Bombycidae/Moraceae
VISCOSE RAYON
Dissolving wood pulp cellulose in sodium hydroxide soln and treating with carbon disulphide SODIUM HYDROXIDE TREATED WITH CARBON DISULPHIDE
ALGINATES
Laminaria hyperborea, other sp, Ascophyllum comes from cell walls of brown algae
Absorbable sutures classification: __
1 Catgut 2 Collagen 3 Cargile membrane 4 Kangaroo tendon 5 Fascia lata (from thigh) CCCKF
1 Made up of materials which resist enzymatic digestion, remain in the body to be removed after wound healing. 2 Examples
1 Non-absorbable suture material 2 Silk ,cotton, nylon, linen stainless steel metallic
For automatic tissue penetration
Ultra sharp needle point
Provides maximum strength and smoothness
Silicone-coated Stainless Steel Needle
Sources of Crude Drugs
Animals Plants Minerals
Mineral Deposits of Different types
1 Terrestrial deposits 2 Fossil deposits (geological origin in oceans and seabeds)
Collection of Mineral Deposits
By mining in open quarries Further purified for various pharmaceutical uses
Kaolin Identification
Heat kaolin on charcoal black with cobalt nitrate -> Forms Blue Mass (due to Alumina)
Amphibole LIST
1 Amosite (BROWN) 2 Crocidolite - most dangerous (BLUE) 3 Anthophyllite 4 Tremolite 5 Actinolite ACATA 3,4,5: Less Used industrially but found in talcum powders
1 Most widely used substances in baby powder 2 Origin of talc 3 succeeded in exportation overseas
1 Hydrated magnesium silicate or TALC 2 Persian through Arabic talc 3 Indian talc
Talc Properties
The softest known solid, translucent to opaque White to gray to green in color(due to iron oxide) , odorless, tasteless Lubricant, has high luster but low conductivity to heat and electricity thus give its industrial value Chemically inert, sparingly soluble in dilute mineral acid, insoluble in water
Talc Uses
In cosmetics (Talcum powder) ,as lubricant Dusting powder for coating and dusting pills As filler in paper manufacture Astringent in baby powders to prevent rashes Filtering aid in filtration and clarification of cloudy liquids
Bentonite Properties
Slightly greenish gray or blue, shows a light blue under the UV light Insoluble in water, HCl and H2SO4 Hexagonal crystals microscopically
Bentonite Uses
1 As gemstone due to its hardness 2 As base in gels,ointments,lipsticks, depilatories and rouge 3 The less absorbent bentonite chiefly in oil industry 4 As suspending and emulsifying agents and base for plasters
1 is from ancient process of pulling wool to remove oil and dust particles with a water slurry of earth. 2 Source 3 Properties
1 FUELLER’S EARTH Syn: Floridin, Multani, Mitti 2 Mined in open quarry, it is a nonplastic type of kaolin Contains aluminum-magnesium silicate 3 White to yellowish gray, odorless, tasteless powder, swells and acquire nonplastic texture in water.
Fueller's Earth Uses
1 Decolorizer for oils and other liquids 2 Clarifying and filtering agent 3 For cleansing of woolen fabrics 4 Used in preparation of dusting powders due to its absorbency
Source: a native form of calcium carbonate purified by elutriations
PREPARED CHALK Syn: Chalk, Creta, Paris-White, Whiting, English White
PREPARED CHALK COLLECTION
Mined in open quarry, pulverized and purified by elutriation The water is removed and the insoluble chalk is settled forming flat cakes known as “whiting” Further purified for pharmaceutical use
PREPARED CHALK properties
Colorless, odorless, white earth, soft to touch Amorphous and insoluble in water Effervesce with acids
PREPARED CHALK USES
Antacid, antidiarrheals Dietary supplement Dusting powder Abrasive in tooth powders & toothpastes Used in manufacture of antibiotics
1 Kiesulgher Properties 2 USES
1 Brownish-gray to white light powder Odorless, tasteless Smooth and adheres to skin after rubbing, absorbs moisture but not slippery Does not swell in cresol 2 Filtering medium For clarification and decoloring of liquids In manufacture of tooth powders, face powders and nail polish
1 Calamine USES 2 Calamine PROPERTIES
1 Uses: Topical astringent and skin protectant Ingredient of lotions and cosmetics 2 Odorless,colorless to light pink, very fine Insoluble in water, soluble in mineral acids Contains 99% zinc oxide , 0.5% ferric oxide which gives its color Calcium should not be present for pharmaceutical purposes
1 Calamine USES 2 Calamine PROPERTIES
1 Uses: Topical astringent and skin protectant Ingredient of lotions and cosmetics 2 Odorless,colorless to light pink, very fine Insoluble in water, soluble in mineral acids Contains 99% zinc oxide , 0.5% ferric oxide which gives its color Calcium should not be present for pharmaceutical purposes
1 Calamine USES 2 Calamine PROPERTIES
1 Uses: Topical astringent and skin protectant Ingredient of lotions and cosmetics 2 Odorless,colorless to light pink, very fine Insoluble in water, soluble in mineral acids Contains 99% zinc oxide , 0.5% ferric oxide which gives its color Calcium should not be present for pharmaceutical purposes
1 Calamine USES 2 Calamine PROPERTIES
1 Uses: Topical astringent and skin protectant Ingredient of lotions and cosmetics 2 Odorless,colorless to light pink, very fine Insoluble in water, soluble in mineral acids Contains 99% zinc oxide , 0.5% ferric oxide which gives its color Calcium should not be present for pharmaceutical purposes
1 Calamine USES 2 Calamine PROPERTIES
1 Uses: Topical astringent and skin protectant Ingredient of lotions and cosmetics 2 Odorless,colorless to light pink, very fine Insoluble in water, soluble in mineral acids Contains 99% zinc oxide , 0.5% ferric oxide which gives its color Calcium should not be present for pharmaceutical purposes
1 Calamine USES 2 Calamine PROPERTIES
1 Uses: Topical astringent and skin protectant Ingredient of lotions and cosmetics 2 Odorless,colorless to light pink, very fine Insoluble in water, soluble in mineral acids Contains 99% zinc oxide , 0.5% ferric oxide which gives its color Calcium should not be present for pharmaceutical purposes
1 Calamine USES 2 Calamine PROPERTIES
1 Uses: Topical astringent and skin protectant Ingredient of lotions and cosmetics 2 Odorless,colorless to light pink, very fine Insoluble in water, soluble in mineral acids Contains 99% zinc oxide , 0.5% ferric oxide which gives its color Calcium should not be present for pharmaceutical purposes
1 Calamine USES 2 Calamine PROPERTIES
1 Uses: Topical astringent and skin protectant Ingredient of lotions and cosmetics 2 Odorless,colorless to light pink, very fine Insoluble in water, soluble in mineral acids Contains 99% zinc oxide , 0.5% ferric oxide which gives its color Calcium should not be present for pharmaceutical purposes
1 Calamine USES 2 Calamine PROPERTIES
1 Uses: Topical astringent and skin protectant Ingredient of lotions and cosmetics 2 Odorless,colorless to light pink, very fine Insoluble in water, soluble in mineral acids Contains 99% zinc oxide , 0.5% ferric oxide which gives its color Calcium should not be present for pharmaceutical purposes
1 Calamine USES 2 Calamine PROPERTIES
1 Uses: Topical astringent and skin protectant Ingredient of lotions and cosmetics 2 Odorless,colorless to light pink, very fine Insoluble in water, soluble in mineral acids Contains 99% zinc oxide , 0.5% ferric oxide which gives its color Calcium should not be present for pharmaceutical purposes
1 Calamine USES 2 Calamine PROPERTIES
1 Uses: Topical astringent and skin protectant Ingredient of lotions and cosmetics 2 Odorless,colorless to light pink, very fine Insoluble in water, soluble in mineral acids Contains 99% zinc oxide , 0.5% ferric oxide which gives its color Calcium should not be present for pharmaceutical purposes
1 Calamine USES 2 Calamine PROPERTIES
1 Uses: Topical astringent and skin protectant Ingredient of lotions and cosmetics 2 Odorless,colorless to light pink, very fine Insoluble in water, soluble in mineral acids Contains 99% zinc oxide , 0.5% ferric oxide which gives its color Calcium should not be present for pharmaceutical purposes
Shines brightly
Mounted in cresol and observed in dark polarized light
Permanent red stain
Bentonite +1% safranin in 70% alcohol
Deep blue color
Bentonite + 0.1% methylene blue
Calamine 1 Source and 2 Use
1 Hemimorphite 2 Cosmetics
Kaolin 1 Source and 2 Use
1 Feldspar deposits 2 Gastric Agents
Asbestos 1 Source and 2 Use
1 Hornblende 2 Bacterial Filter