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Principles of pharmacology

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Pregunta:

Phase 2 metabolism summary purpose and processes

Autor: Gen Bailey



Respuesta:

Purpose: Attach a large, water-soluble molecule to the drug or its Phase 1 product to enhance excretion via urine or bile. Key Processes: Glucuronidation: Addition of glucuronic acid (most common). Sulfation: Addition of a sulfate group. excretion. Phase 2 reactions are catalysed by TRANSFERASE ENZYMES


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