How is allergic contact dermatitis?

➢ DTH responses in the skin can also occur as contact hypersensitivity (CH) ➢ Allergic contact dermatitis (ACD) is a common inflammatory skin disease presenting with pruritic, eczematous lesions. ➢ ACD is common in the general population and is the most frequent occupational skin disease ➢ Its etiology may be suggested by the body sites of involvement, history of exposure, and morphology and distribution of the skin lesions. ➢ ACD results from a T cell-mediated, DTH reaction elicited by the contact of the skin with the offending chemical in individuals who have been previously sensitized to the same chemical