Newer drugs affect on shizophrenia

Newer atypical drugs are reported to improve some of the negative symptoms of schizophrenia, including emotional blunting, social withdrawal, and lack of motivation ambivalence, and reduced ability to relate to people The “negative” symptoms, such as blunted affect, anhedonia, apathy, and impaired attention, as well as cognitive impairment, are not as responsive to therapy, particularly with the first-generation antipsychotics. Many second-generation agents, such as clozapine, ameliorate the negative symptoms to some extent.