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CNS Pharmacology

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Pregunta:

5. Discontinuation syndrome:

Autor: Suzuki



Respuesta:

Whereas all of the SSRIs have the potential for causing a discontinuation syndrome after their abrupt withdrawal, the agents with the shorter half-lives and having inactive metabolites have a higher risk for such an adverse reaction. Fluoxetine has the lowest risk of causing an SSRI discontinuation syndrome. Possible signs and symptoms of such a serotonin-related discontinuation syndrome include headache, malaise and flu-like symptoms, agitation and irritability, nervousness, and changes in sleep pattern.


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Autor

Suzuki
Suzuki