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Clinical Immunology

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Pregunta:

How is mechanism of action of RNA-based vaccines Moderna and Pfizer COVID?

Autor: H K



Respuesta:

MRNA encoding the target protein only, enclosed in a lipid nanoparticle The mRNA is injected in muscle cells -> It is translated in target protein , then disintegrates afterwards -> Large numbers of target protein molecules are produced by the cell and recognized by B and T cells -> The immune system makes protein-specific antibodies and Cytotoxic T cells and is ready to make more if it encounters the virus


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Autor

H K
H K