How was Hep B recombinant vaccine?

— Preparation and composition of the vaccine: — Cloning of the gene encoding the HBsAg in yeast cells — Purification of HBsAg from lysed cells — Addition of an adjuvant to the vaccine preparation (aluminium hydroxyde = alum) — Commercial names : — Engerix B, Recombivax HB (Merk); …. — Comvax: combined HBV and Hib vaccine — Efficacy: Induces production of protective anibodies