Pregunta:
What are some examples of polysaccharide conjugated to protein vaccines?
Autor: H KRespuesta:
Hib vaccine: Polysaccharides conjugated to a protein carrier • The polysaccharide (PS) alone may activate B in a Tindependent manner, without memory • PS conjugated to a carrier protein (tetanus or diphtheria toxoid) induces a T-dependent antibody response with memory Vaccine against hepatitis B virus History: HB virus discovered in 1965 (Australia Antigen) 1st vaccine (1969): inactivated virus purified from serum of infected individuals 2nd vaccine (1986): recombinant protein prepared by genetic engineer
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