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Clinical Immunology

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Pregunta:

What are bacterial vaccines based on purified toxoids?

Autor: H K



Respuesta:

— Exotoxins of Clostridium tetani and Corynebacterium diphtheriae are responsible of their pathogenicity — Toxoids are modified non pathogenic exotoxins — Neutralizing anti-toxoid antibodies are efficient in preventing intoxication Toxins enter cells via cellular receptors, then dissociate releasing active chain which poison cells, protected by Ab blocking the toxin.


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Autor

H K
H K