What are TCAs?

Block a1 Rs (othrostatic hypotension and dizziness) Histaminic Rs (sedation and weight gain) and Muscarinic Rs (blurred vision, xerostomia, constipation, urinary retention) Include (3ary amines (Imipramine [controls bed wetting children], amitryptiline, Clomipramine. 2ary Amines (Desipramine [block NE reputake], Maprotiline, Amoxapine [block DA Rs])