What is aGVHD therapy?

Primary (Mild disease: limited skin rash alone Optimize tacro or CSP levels, topical steroids If progressive or multisystem Prednisilone 2mg/kg/d Steroid Refractory aGVHD (no response 3-7d) No clearly superior second regimen ECP, etanercept, infliximab, pentostatin Poor prognosis due to infectious complications)