What is reperfusion injury?

Lethal reperfusion injury, which refers to reperfusion-induced death of cells that were s5ll viable at restora5on of coronary blood flow • Vascular reperfusion injury, which is progressive damage to the microvasculature such that there is an expanding area of no-reflow and loss of coronary vasodilatory reserve • Stunned myocardium, in which salvaged myocytes display a prolonged period of contrac5le dysfunc5on aCer restora5on of blood flow because of abnormali5es in intracellular metabolism, leading to reduced energy produc5on • Reperfusion arrhythmias, which refer to bursts of VT (and occasionally VF) that occur within seconds of reperfusion.