What is vasculitis?

Presence of inflammatory leukocytes in vessel walls with reactive damage to mural structures. Muscular arteries may develop focal or segmental lesions and these may be life threatening, Inflammation lead to aneurysm, vessel rupture or segmental lesions causing stenosis, occlusion with distal infarction myabe. Affected vessels vary in size, type, location according to specific types of vasculitis, large or medium or small vessels. Exact pathobiology is unknown and multifacorial, sometimes fatal diseases that require prompt recognition and therapy, may get symptoms either isolated or multisystem.