TOXICOLOGY: Serotonergic Toxidrome
→ Collection of signs and symptoms produced by excess serotonin in the central, peripheral, and autonomic nervous system

→ Selective serotonin reuptake (paroxetine and fluoxetine), Serotonin noradrenaline reuptake inhibitors (venlafaxine and citalopram), Tricyclic antidepressants, Monoamine oxidase inhibitors (moclobemide)– blocks serotonin breakdown, Analgesic (pethidine, tramadol, fentanyl), Antiemetics (metoclopramide and ondansetron), Anticonvulsants (valproic acid), Dietary
supplements (ginseng and st. john’s wort)

GIVE THE MANIFESTATIONS OF THIS POISONING

Question

Serotonergic Toxidrome
→ Collection of signs and symptoms produced by excess serotonin in the central, peripheral, and autonomic nervous system

→ Selective serotonin reuptake (paroxetine and fluoxetine), Serotonin noradrenaline reuptake inhibitors (venlafaxine and citalopram), Tricyclic antidepressants, Monoamine oxidase inhibitors (moclobemide)– blocks serotonin breakdown, Analgesic (pethidine, tramadol, fentanyl), Antiemetics (metoclopramide and ondansetron), Anticonvulsants (valproic acid), Dietary
supplements (ginseng and st. john’s wort)

GIVE THE MANIFESTATIONS OF THIS POISONING

LEIGHTON DWIGHT OBILLOS · Accepted Answer

Manifestation: wide variation of signs and
symptoms, 
dysfunction of areas in nervous system, 
tremor, 
hyperreflexia, 
muscle rigidity,
clonus (involuntary or rhythmic muscular contraction and relaxation), 
fever, 
tachycardia,
hypertension

TOXICOLOGY

Manifestation: wide variation of signs and symptoms, dysfunction of areas in nervous system, tremor, hyperreflexia, muscle rigidity, clonus (involuntary or rhythmic muscular contraction and relaxation), fever, tachycardia, hypertension

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