1 concerns include costs, prices, charges, and payment levels associated with individual technologies. Other issues: comparisons of resource requirements and outcomes (cost effectiveness, cost utility, and cost benefit) 2 impacts on: a nation’s gross domestic product, national health care costs, and resource allocation across health care and other industrial sectors, and international trade. Other issues: effects of intellectual property policies, regulation, third-party payment, other policy changes affecting technological innovation, adoption, diffusion, and use.