What are anatomical clinical correlations of plaque?

➢The clinical manifestations related to the presence of atherosclerotic plaque are very inconsistent and the correlations are imprecise, making it difficult to predict clinical manifestations based on the size and evolution of a plaque. ➢Schematically, uncomplicated stenotic plaques (> or = 70% in the coronary territory) are associated with symptomatology appearing on exertional stress (exertional angina, intermittent claudication). ➢Complicated plaques are responsible for paroxysmal symptomatology and clinical accidents: myocardial infarction, sudden death, resting angina, stroke for example. ➢But these manifestations are inconsistent and a complicated plaque can remain asymptomatic.