What are some vascular pathologies?

When blood passes through capillaries plasma proteins are retained in vascular system and there is a little movement of water and electrolytes in tissues, this balance may be disturbed by pathological conditions (altered endothelial function, increased hydrostatic pressure, or decrease in plasma protein content), all these promote edema (fluid accumulation in tissues from sharp movement of water extravascular. Edema may be minimal to severe, in lower limb discomfort, in lung life threat, trauma compromises structural integrity, hemostasis in blood prevents excessive bleeding after vessel damage. Inadequate hemostasis can lead to hemorrhage can lead to hypotension, shock and death. Impaired clotting can lead to ischemia (MI, PE, stroke)