What are cancer genes?

Genes affected by genetic aberration in cancer, could be acquired by environment, may occur spontaneously or germ line, numerous, 4 classes (oncogenes, tumor suppressor genes, apoptosis regulation genes, genes regulating interaction between cancer and normal cells. Oncogenes (increase cell growth), tumor suppressor (prevent uncontrollable growth) Regulate apoptosis (enhancing cell survival), Interaction genes (tumor recognition by immune system) Mostly acquired through life, but some are germ line (RB, TP53, CDKN2A, APC, NF1, NF2, MEN, RET, BRCA, MSH, PTCH..autodominant),(xeroderma pig, ataxia ATM, bloom BLM, Faconi anemia auto recessive)