What is neoplasia in general?

Cancer is caused by DNA mutation, done by exposure to mutagen or aging, we have epigenetic changes (methylation, histone modification) so different expression (growth, survival and senescence), genetic alterations in a cell are heritable to its daughter cells (Clonal) Neoplasia (new growth) are cells that replicate w/out regulatory influences that act on mother cells that are normal (autonomous cells and increase in size regardless of environment) Neoplasm = tumor and relies on host nutrition and blood supply, some are benign and some are malignant