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Pharmacology

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Pregunta:

Give examples on receptor down and up-regulation?

Autor: H K



Respuesta:

Downregulation in case of prolonged agonists (chronic use of salbutamol (adrenergic agonist) down regulated beta-receptors- decreased effect of salbutamol in asthmatic pt)) Upregulation in case of prolonged antagonist effect (withdrawal of beta blockers (propranolol) suddenly, causes withdrawal symptoms anxiety palpitation tachycardia, htn,


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1 answer(s) in total

Autor

H K
H K