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BIOPHARMACEUTICS

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Pregunta:

Why are drug concentrations more often measured in plasma rather than whole blood or serum?

Autor: LEIGHTON DWIGHT OBILLOS



Respuesta:

It is the most direct approach to assess the pk of drug in the body PLASMA perfuses all the tissues of the body, including the cellular elements in the blood Small molecules in the blood are carried thru the plasma Changes in the drug concentration in plasma will reflect changes in tissue drug concentrations. Measuring the plasma drug level is a responsive method of monitoring the course of therapy.


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