Glycoside Properties

(1) Glycoside contains sugar but still the physical , chemical, & therapeutic activity is based on aglycone portion. Sugar facilitates the absorption of the glycoside helping it to reach the site of action. (2) Crystalline, amorphous substance which are soluble in water and dilute alcohol but insoluble in chloroform and ether. The aglycone moiety is insoluble in nonpolar solvent like Benzene (3) Easily hydrolyzed by mineral acids, water, and enzyme (4) Cannot reduce Fehling’s solution until they are hydrolyzed (5) They show optical activity normally they are levorotatory.