Can be use with Pen allergy active against aerobic bacteria, gram -ve bacilli> E.coli, K. pneumoniae, P. mirabilis, S. marcescens, Citrobacter spp binds with high affinity to PBP 3 in gram -ve only inactive against gram + and anaerobes Urinary and Respiratory infections, intra-abdominal infections, gynecological infections Given IV. Excreted through Renal