What's BADASP (Burst After Duplication with Ancestral Sequence Predictions )?

• Developed by Richard Edwards in 2005 • Identifies residues under both type I and type II divergence • In addition to residues implicated in functional divergence (i.e., those under positive selection), identifies residues under consistent purifying (negative) selection, which may be important for common functionality between all sequences/subfamilies. • Implemented in SeqSuite software package