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PCOG LAB FINALS


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are esters of long-chain fatty acids and alcohol, or of closely related derivatives form the bulk of the organic matter of living cells refers to substances which have in common the property of being insoluble in water and soluble in organic solvents heterogenous group of compounds which are widely distributed in nature
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Lipids (fixed oils, fats, and waxes)

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PCOG LAB FINALS - Marcador

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PCOG LAB FINALS - Detalles

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Differentiate 1 Fixed oils and fats 2 Waxes
1 in fixed oils and fats, glycerol combines with the fatty acids 2 in waxes, the alcohol has a higher molecular weight
1 Fats and fixed oils are obtained from __ 2 Fats and fixed oils primary function
1 plants (olive oil, peantut oil) animals (lard) 2 food (energy) storage
List of fixed oils obtained from seeds
Cottonseed, linseed, sesame seed, rapeseed, coconut, castor beans, almond
Lipids are classified as __
1 neutral lipids (fats and waxes) 2 Phospholipids (phophates and shingolipids) 3 lipoproteins (lipid material in mammalian plasma) 4 glycolipids (carbohydrate- glyceride derivatives which do not contain phosphate)
From what parts of the plant are olive oil and corn oil obtained
Olive oil: flesh of fresh olives Corn oil: germ (embryo) of the kernel
1 What is poppyseed oil? 2 In what official drug it is used?
1 Poppyseed oil is an edible oil obtained from poppy seeds. Highly palatable, rich in vitamin E. 2 Morphine, Codeine, Heroin, Oxycodone
To what group of plants does Lycopodium belong
Genus clubmosses Family Lycopodiaceae
What fatty acids are present in the fixed oil found in Lycopodium
1 Linoleic acid 2 Oleic acid 3 Palmitic acid
1 What is meant by polymorphic? 2 Name and compare the polymorphic forms of Cocoa Butter.
1 Ability to display different structures of a substance. 2 γ (16-18 °C) α (21-24 °C) β1 (27-29 °C) β (34-35 °C) β2 (36-37 °C)
What is benzoinated lard? compare with lard
1 Benzoinated lard contains 1% benzoin, used as lubricant, soap, illuminant, oiling wool. 2 Lard refers to product obtained and rendered from animal fat, particularly pork meat.
What are the uses of Lanolin and Anhydrous Lanolin?
Anhydrous lanolin: Moisturizer, treat or prevent dry, rough, scaly, or itchy skin. Lanolin: Treat or prevent minor skin irritations such as blisters, burns, dry skin, and diaper rash
What are the constituents of Spermaceti? Why does the USP monograph include a test to detect the presence of stearic acid?
1 Cetyl palmitate with smaller quantities of cetyl myristate, cetyl laurate, and cetyl stearate. 50-63% wax alcohols 2 TO determine if it caused adulteration to the product
Describe White Wax NF / Yellow Wax USP
Yellowish-white solid Translucent in thin layers Faint characteristic odor Free from rancidity Used as Stiffening agent, Thickener, Emulsifier
White Wax / Yellow wax uses
Stiffening agent, Thickener, Emulsifier
Coconut oil (SN, USES)
Cocos nucifera, Arecaceae Treat eczema, treat psoriasis, obesity, anti cancer
Palm oil (SN, USES)
Arecaceae Anti malarial, heart disease, anti cancer, treat vitamin A deficiency
Sesame oil (SN, USES)
Sesamum indicum, Pedaliaceae Anti inflammatory, Regulate blood sugar, stress and depression relief
Mustard oil (SN, USES)
Brassica juncea, Cruciferae Stimulant, reduce cold and cough, cardioprotective, Relief from joint pain and arthritis
Coconut oil active constituents
Salicylic acid syringic acid caffeic acid catechin
Removal of the oils may take the form of __
Cold or hot expressions, centrifuging or solvent extraction depending on the commodity
1 Peanut oil is also known as __ 2 Peanut oil is obtained from the seeds of __
1 Arachis oil 2 Arachis hypogaea (Legumunosae) (earth-nut, ground-nut, peanut) by soxhlet extraction or expression
Arachis or peanut oil consists of
1 oleic, 2 linoleic, 3 palmitic, 4 arachidic, 5 stearic, 6 lignoceric and other acids
1 Peanut oil refractive index 2 Peanut oil specific gravity 3 Peanut oil appearance
1) 1.462 - 1.464 2) 0.912 - 0.920 3) Pale yellow liquid, Faint characteristic odor, Bland taste
What are the differences between the fixed oils and volatile oils?
Volatile oils vaporize easily at room temperature volatile oils are aromatic Fixed oils does not vaporize easily at room temperature fixed oils are rancid
Chemical Tests for fixed oils list
1 Iodine no. 2 Saponification no. 3 Reichert-Meissl (RM) number 4 Acid no.
What causes the rancidity of the fixed oils?
Oxidation of unsaturated fatty acids accelerated when exposed to light, heat and air
Name the pharmaceutical uses of peanut oil.
Lower cholesterol Prevent Heart Disease Aid in weight loss Prevent cancer
Volatile oil may occur in specialized secretory structures such as __
1 glandular hairs (Lamiaceae) 2 modified parenchymal cells (Piperaceae) 3 oil-tubes called vittae (Apiaceae) 4 lysigenous or schizogenous passages (Pinaceae, Rutaceae)
Chemical constituents of volatile oil and spices may be divided into two broad classes:
1) terpenoid derivatives formed via acetate-mevalonic acid pathway 2) aromatic compounds formed via the shikimic acid-phenylpropanoid.
The chief advantage of extraction over distillation __
Uniform temperature (usually 50˚C) can be maintained during most of the process
What is the chief source of citral?
1 Lemongrass oil (75% to 80%) 2 Citrus spp.
Describe the process utilized in the recovery of Lemon oil. What other oils may be obtained by theses processes?
Lemon oil can be obtained by expression process. Other oils obtained from this process is Citrus oils and Orange oils
Name the kinds of eucalyptus oils available in commerce. What are the chief constituents of each kind? Give at least two species yielding each type of oil.
Eucalyptus globulus oil (oxide &monoterpene) Eucalyptus Radiata oil (oxides&monoterpenol) Eucalyptus citriodora oil (aldehyde) Eucalyptus dives oil (ketone&monoterpene)
1 Give the botanical garden and habitat of Canella bark. 2 What other names are used for this drug? 3 What are the principal constituents of its oil and what is the bark used for?
1 native to the Caribbean from the Florida Keys to Barbados. 2 Cinnamon bark, Wild cinnamon 3) 1,8 cineole, terpinen-4-ol, a terpinyl acetate, a terpinol. Uses: Tonic, for toothaches, for cold, for blood circulation
What is Bay Laurel? Give the botanical origin, habitat, and uses.
Aromatic evergreen plant with glabrous leaves Belongs to the family Lauraceae Native to the Mediterranean region of southern Europe, the Middle East, Western Asia, and North Africa
1 What other volatile oil contains safrole as the principal ingredient? 2 What precautions should you take regarding its use?
1 Brown camphor oil, Yellow camphor oil 2 Not to be used on broken skin or injured skin because its toxicity will be absorbed. Can cause respiratory problems such as coughing and wheezing when inhaled
Name other natural sources of camphor
Obtained from Borneo Camphor Tree, East African Camphor Wood Tree, Camphor Laurel Tree
List other official and non ofiicial preparations containing camphor as an ingredient. What is each preparation used for?
Tiger balm, analgesic Vicks, cough reliever Bengay, pain and aches Icy hot, pain reliever Biofreeze, pain reliever
What is Blue Flag? Where is its habitat, and what is its active constituent?
1 A native herb found in eastern and central canada. People use blue flag for conditions such as bloating, swelling (inflammation), fluid retention, liver problems 2 Triterpinoids, Oleoresin, salicylic acid, isophthalic acid
Describe the process enfleurage
A technique that extracts scents and oils from plants. The advantage of this technique is that even the most fragile plants can be used.
Give the rationale behind the absorption of essential oil in fats
Because of their solubility in the lipids found in the stratum corneum, lipophilic substances (such as essential oils) are considered to be easily absorbed.
Characteristics of Peptide bond
It is planar (the atoms in the bond lie on the same plane) It is achiral ( does not have a mirror image) It is relatively rigid It is polar It is good hydrogen bond donor
Characteristic of Resins
Hard, transparent or translucent
Properties of Alkaloids
Basic, Bitter taste, Heterocyclic structure. are naturally occurring organic compounds containing one or more nitrogen atoms, frequently in a heterocyclic ring, which possess marked physiologic activity
Characteristics of Volatile Oils
Odorous principle found in various plant parts Evaporate when exposed to the air at ordinary temperatures, Are called volatile oils, ethereal oils, or essential oils. possess characteristic odors Optically active Immiscible with water Soluble in ether, alcohol, and most of the organic solvents. Their specific rotation is often a valuable diagnostic property
Volatile oil may occur in specialized secretory structures:
1 Glandular hairs (Lamiaceae) 2 Modified parenchymal cells (Piperaceae) 3 Oil-tubes called vittae (Apiaceae) 4 Lysigenous or, Schizogenous passages (Pinaceae,Rutaceae)
Chemical constituents of volatile oil and spices may be divided into two broad classes, based on their biosynthetic origin
(1) terpenoid derivatives formed via acetate-mevalonic acid pathway (2) aromatic compounds formed via the shikimic acid-phenylpropanoid.
Sources of Chili - USP 25
Capsicum annuum Capsicum frutescens Capsicum chinense Capsicum pubescens
What causes rancidity of Fixed Oil
Exposure to oxygen, presence of light, high temperature, and presence of moisture
Chief source of citral
Lemongrass (Cymbopogon citratus)
Characteristic of Gum
1 Hydrophilic 2 Viscous
What is albumin ( in plants and its proteins)
Are probably not storage proteins Are characterized by solubility in water and in dilute aqueous solutions of salts, acids, and alkalies. And by heat coagulability. They are precipitated from solution by a saturated solution of ammonium sulphate or similar electrolyte. Proteins in this class are found widely distributed in living material. Many have been obtained in crystalline form. The beta-amylase of barley and legumelin of soybean and examples of plant albumins. The toxic principles of some seed are albumins, e.g., oxins of castor bean.