Dendritic Cells (DCs): what are classical and plasmacytoid Role of CCR7/CCR7R in CD migration?

Upon activation by infectious agents dendritic cells produce inflammatory cytokines, and express chemokine receptor CCR7 CCR7 receptor recognize chemoattractants produced by cells in lymph nodes- this direct migration of dendritic cells to lymph nodes and meet T cells (12-18 hours). During this migration dendritic cells mature into APC that express MHC with antigen peptides