Eye uses antimuscarinic agents

Antimuscarinic drugs are used to cause mydriasis, as indicated by the origin of the name belladonna (“beautiful lady”) from the ancient cosmetic use of extracts of the Atropa belladonna plant to dilate the pupils. They also cause cycloplegia and prevent accommodation. In descending order of duration of action, these drugs are atropine (>72 h), homatropine (24 h), cyclopentolate (2–12 h), and tropicamide (0.5–4 h). These agents are all well absorbed from the conjunctival sac into the eye.