1. Actions: Physostigmine

1. Actions: Physostigmine has a wide range of effects as a result of its action, and stimulates not only the muscarinic and nicotinic sites of the ANS but also the nicotinic receptors of the NMJ. Its duration of action is about 2 to 4 hours, and it is considered to be an intermediate-acting agent. Physostigmine can enter and stimulate the cholinergic sites in the CNS.