Buscar
Estás en modo de exploración. debe iniciar sesión para usar MEMORY

   Inicia sesión para empezar


Por supuesto:

CNS Pharmacology

» Iniciar este curso
(Practica preguntas similares gratis)
Pregunta:

Catechol-O-methyltransferase (COMT) Inhibitors Mechanism of action—

Autor: Suzuki



Respuesta:

Entacapone and tolcapone are inhibitors of COMT, the enzyme in both the CNS and peripheral tissues that converts levodopa to 3-O-methyldopa(3OMD). Increased plasma levels of 3OMD are associated with poor response to levodopa partly because the compound competes with levodopa for active transport into the CNS. Entacapone acts only in the periphery.


0 / 5  (0 calificaciones)

1 answer(s) in total

Autor

Suzuki
Suzuki