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CNS Pharmacology

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Pregunta:

1. Tolerance and dependenc ethanol

Autor: Suzuki



Respuesta:

Tolerance occurs mainly as a result of CNS adaptation and to a lesser extent by an increased rate of ethanol metabolism. There is cross-tolerance to sedative hypnotic drugs that facilitate GABA activity (eg, benzodiazepines and barbiturates). Both psychological and physical dependence are marked.


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Autor

Suzuki
Suzuki