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pharmacology chemotherapy

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Pregunta:

Resistance to Anticancer Drugs by formation of trapping agents

Autor: Suzuki



Respuesta:

Some tumor cells increase their production of thiol trapping agents (eg, glutathione), which interact with anticancer drugs that form reactive electrophilic specie This mechanism of resistance is seen with the alkylating agent bleomycin, cisplatin, and the anthracyclines.


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Autor

Suzuki
Suzuki