Buspirone pharmaco and adverse effects

Buspirone is metabolized by CYP3A4, and its plasma levels are markedly increased by drugs such as erythromycin and ketoconazole. Side effects of buspirone include tachycardia, paresthesias, pupillary constriction, and gastrointestinal distress. Buspirone has minimal abuse liability and is not a schedule-controlled drug. The drug appears to be safe in pregnancy.