Ciclopirox

Ciclopirox inhibits the transport of essential elements in the fungal cell, disrupting the synthesis of DNA, RNA, and protein. Ciclopirox is active against Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum canis, Candida albicans, and Malassezia furfur. Ciclopirox 1% shampoo is used for treatment of seborrheic dermatitis. Ciclopirox 0.77% gel is used for treatment of interdigital tinea pedis, tinea corporis, and seborrheic dermatitis. Ciclopirox 8% solution is used for treatment of onychomycosis of nails without lanula involvement. Ciclopirox 0.77% cream and suspension is used for treatment of dermatomycosis, candidiasis, and tinea versicolor.