Standard regimen

For empiric treatment of pulmonary TB (in most areas of <4% INH resistance), an initial 3-drug regimen of INH, rifampin, and pyrazinamide is recommended. If the organisms are fully susceptible (and the patient is HIV-negative), pyrazinamide can be discontinued after 2 month and treatment continued for a further 4 month with a 2-drug regimen. ethambutol can be given with 3 drugs too