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Clinical Immunology

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Pregunta:

What is active cancer immunotherapy?

Autor: H K



Respuesta:

Intended to inhibit immunosuppressive mechanisms and amplify antigen-specific T cell responses Three approaches used : — Checkpoint inhibitors: mAbs antagonists of inhibitory signals — CAR-T cell therapy: Patient treatment with modified autologous T cells — Therapeutic cancer vaccines: Tumor antigens or genes encoding for these Ags, that either activate pre-existing host antitumor immune cells or induce the differentiation of new ones


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Autor

H K
H K