How is CAR-T cell therapy in HIV tx?

— Patient’s T-cells are transfected with both anti-CD4 and anti-HIV envelope protein (E) scFvs — they bind to both CD4 and E proteins on CD4 infected T-cells, inducing their death — The expression of C46 (an HIV-resistance protein) on the surface of the CAR-T-cell prevents the CAR T-cell itself from being infected by the HIV virus