How is rota virus live attenuated vaccine?

— Rotaviruses are responsible of most fatal diarrheas in infants — Naked RNA viruses: 3 protein shells, an outer capsid, an inner capsid and an internal core, surround the 11 segments of ds RNA. — The outer capsid proteins are neutralization antigens : — VP4 (P) is the viral attachment protein: defines the P serotype (11 P serotypes. Main one is P1[8] — VP7 (G) protein is the major outer capsid protein. Defines the G serotype Two live attenuated vaccines are available — Rotarix: monovalent human vaccine. One serotype: P1[8]G1 — Rotareq: pentavalent recombinant bovine-human vaccine. Four viruses express human G of serotypes and bovine P or vice versa