What is tuberculin test?

➢ A classic example of delayed type IV HS is the Mantoux tuberculin test. ➢ Small amounts of tuberculin—a complex mixture of peptides and carbohydrates derived from M. tuberculosis—are injected intradermally ➢ The tuberculin test is used to determine whether an individual has previously been infected with Mycobacterium tuberculosis (A previously infected individual would harbour reactive T cells in the blood). ➢ In individuals who have previously been exposed to the bacterium, either by infection with the pathogen or by immunization with BCG, an attenuated form of M. tuberculosis, a local T cell-mediated inflammatory reaction evolves over 24–72 hours