What is end result of arthus reaction?

Further aggregation of immune complex-related processes induce a local fibrinoid necrosis with ischemia-aggravating thrombosis in the tissue vessel walls. ➢ The end result is a localized area of redness and induration that typically lasts a day or so; Arthus reaction. ➢ Platelet aggregation, especially in microvasculature, can cause localized clot formation, leading to blotchy hemorrhage ➢ After an insect bite, a sensitive individual may have a rapid, localized type I reaction at the site. ➢ Often, some 4-8 h later, a typical Arthus reaction also develops at the site, with pronounced erythema and edema (localized vasculitis). Reported for vaccines of Diphtheria and tetanus, severe pain, swelling, induration, edema, hemorrhage necrosis