How is leukocytoclastic vasculitis in TIIIHS?

➢ Leukocytoclastic vasculitis (LCV), also known as hypersensitivity vasculitis and hypersensitivity angiitis, is a histopathologic term commonly used to denote a small-vessel vasculitis ➢ Histologically, LCV is characterized by leukocytoclasis, which refers to vascular damage caused by nuclear debris from infiltrating neutrophils. ➢ LCV classically presents as palpable purpura. Less common clinical findings include urticarial plaques, vesicles, bullae, and pustules. ➢ Cutaneous lesions of LCV are often asymptomatic, but may be associated with pruritus or pain