How is Bullous pemphigoid?

➢ Bullous pemphigoid also is a type II HS disorder in which binding of autoantibodies to basement membrane zone components creates a cleft between the basal layer of the epidermis and the basement membrane, resulting in a subepidermal blister. ➢ Immunofluorescence stains show shows usually C3 and IgG deposition in the basement membrane zone.