What are considerations to institute ECMO therapy?

• Likelihood of organ recovery: appropriate if disease process is reversible with therapy and rest on ECMO. • Cardiac recovery: to either wait for - cardiac recovery (bridge to recovery) - implanting a longer-lasting device (LVAD: bridge to therapy) - transplantation (bridge to transplantation) • Disseminated malignancy. • Advanced age. • Graft vs. host disease. • Known severe brain injury. • Unwitnessed cardiac arrest or cardiac arrest of prolonged duration.