How is staging of mesothelioma?

• Stage I: Tumor confined within the the parietal pleura, i.e., involving only ipsilateral pleura, lung, pericardium, and diaphragm. • Stage II: Tumor invading chest wall or involving mediastinal structures, e.g., esophagus, heart, opposite pleura Lymph node involvement within the chest. • Stage III:Tumor penetrating diaphragm to involve peritoneum; involvement of opposite pleura Lymph node involvement outside the chest. • Stage IV: Distant blood-borne metastases