What is cholangiocarcinoma?

An uncommon tumor that may occur anywhere along the intrahepatic or extrahepatic biliary tree but is most commonly located at the bifurcation (Klatskin Tumor) of the right and left hepatic ducts (60–70% of cases). Nearly all are adenocarcinomas (Over 95%). INCIDENCE Increases with age with peak at 55 to 70 years. 1/100,000 people per year. The male-to-female ratio is 1.3:1. RISK FACTORS Choledochal cyst, ulcerative colitis, sclerosing cholangitis, toxins, contrast dye, hepatolithiasis, biliary-enteric anastomosis