How is dx of sclerosing cholangitis?

SIGNS AND SYMPTOMS Many patients are asymptomatic at the time of diagnosis, but symptoms can include fever, weight loss, fatigue, pruritus, jaundice, hepatomegaly, splenomegaly, and hyperpigmentation. DIAGNOSIS ERCP/PTC reveal a “beads on a string” appearance of the bile ducts (alternating strictures and dilation) inside and/or outside the liver. ALP is almost always elevated. MRCP (less aggressive) Liver Biopsy (if available)