What are functions of spleen?

1. Phagocytosis of blood cells and particulate matter. 2. Antibody production against microbial polysaccharides, as well as autoantibodies against a variety of self antigens. 3. Hematopoiesis. the spleen can become a major site of compensatory extramedullary hematopoiesis in the setting of severe chronic anemia and in patients with myeloproliferative disorders. 4. Sequestration of formed blood elements.