What is richter syndrome?

Transformation of a CLL or SLL into an aggressive lymphoma, primarily diffuse large B cell lymphoma )DLBCL), or rarely into Hodgkin lymphoma • Occurs in approximately 2 - 10% of patients with chronic lymphocytic leukemia • May occur during various times after diagnosis •Sudden clinical deterioration, Development of systemic symptoms (B symptoms), Rapid, asymmetrical lymph node growth