How is pemphigus tx?

• Therapy must be tailored for each patient, taking into account preexisting and coexisting conditions • Corticosteroids (1 mg/kg/d) have improved overall mortality, but now much of the mortality and morbidity in these patients relates to the adverse effects of therapy • Immunosuppressive drugs (eg. Azathioprine) are steroid sparing and should be considered early in the course of the disease • EGF may speed healing of localized lesions. • Rituximab as 1st or second-line therapy • The anti-TNF drugs, sulfasalazine and pentoxifylline have been reported as effective adjunctive treatments • Dapsone has been suggested as a steroid-sparing agent in the maintenance phase of PV • Intravenous Ig therapy