How is pathology of pancreatic cancer?

Precursor lesion (Pancreatic intraepithelial neoplasia ,PanIN-1A  PanIN-1B  PanIN-2  PanIN-3, more genes mutation  , more progressive atypia &Arch. disarray, Goal : to improved ability to detect of these lesion) Location: 66% in Head and Uncinate Process, Dx earlier , Symptomatic,15% in Body, 10% in Tail , Usually larger & more progress at time of Dx, Asymptomaic, Other diffuse involvement Cell types (ductal adenocarcinoma 75%, adenosquamous carcinoma poor prognosis, acinar cell carcinoma uncommon larger tumor >10cm better prognosis)