What is gastrinoma?

Zollinger-Ellison syndrome (ZES) abdominal pain, peptic ulcer disease, and severe esophagitis Suspected if : multiple ulcers Fail response to PPI Ulcer in abnormal location Severe Esophagitis PU without H.pylori or Hx NSAID If no Hx PU , Suspected if +ve Hx MEN-1 in family + Hx PU almost whole family Unexplained Diarrhea (due to Hyper acidity) Unexplain Steatorrhea Hypercalcemia EGD : found Prominent Gastric /Duodenal fold